Halfway as a result of his occupation, Cees Dekker reinvented himself. After several years of hardcore physics, he shifted his concentrate to ‘nanobiology’ for the flip with the millennium. A term he coined himself, being a matter of simple fact.
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Across the similar time, the team of Paul McEuen, who was then primarily based for the College of California, Berkeley, showed related effects on ropes of bundled nanotubes. Based on the wrapping angle, nanotubes can can be found in metallic or semiconducting variants, a prediction that we and Charles Lieber’s team at Harvard College independently verified utilizing scanning tunnelling spectroscopy experiments.
Sculpting nano-electrodes by using a transmission electron beam for electrical and geometrical characterization of nanoparticles.
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial cell division; and initially at any time study in the dynamics DNA supercoils and the invention of supercoil hopping
Example (three) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is revealed in grey, the rim of the pore is highlighted in pink, as well as a 3D rendering of the movement from the DNA rod is exhibited.
Many related developments followed, where our group established different transistor variants like single-electron transistors at room temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled numerous transistors into little proof-of-basic principle Digital circuits.
2011, initial in vitro measurements of https://www.ceesdekker.net transport throughout one biomimetic nuclear pore advanced; progress of multiplexed magnetic tweezers for kilo-molecule experiments; and solved the mechanism of homology recognition in DNA homologous recombination
Understanding fundamental processes regulating the spatial and dynamic organisation in the DNA in live cells.
But carbon nanotubes have remained a investigate subject matter of appreciable fascination to a lot of. Without a doubt, the outlook on employing carbon nanotubes to construct sensible gadgets, in areas such as radio-frequency electronics, electronic electronics and versatile electronics, stays vibrant.
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
Lots of new phenomena have been found, and he and his investigate group founded a leading position With this area of study. Dekker and his investigate group found out new physics of nanotubes and also explored the feasibility of molecular electronics. In 1998, they were the 1st to build a transistor based upon just one nanotube molecule.
One example is, we consider the nucleopore complicated, a gateway concerning the mobile nucleus as well as the cytoplasm. This is a very sophisticated technique and so difficult to analyze in the cell, so we use biomimetics. We reconstruct holes after which you can insert particular person factors in the nucleopore complex to check transport as a result of it at The only-molecule amount.’
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij fulfilled enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever design and style in 2005. (nl)